All About Histamine – 31 Surprising Roles of Histamine, Histamine Receptors and Histamine Metabolism
Histamine is widely known as a substance that contributes to allergies, asthma, eczema, and coughs. In addition, histamine is also a neurotransmitter with very important roles both in the brain and in the gut. Read this post to learn more about histamine. Introduction Histamine is a biogenic amine ( R , R ). Its name is derived from the Greek word ‘histos’, meaning tissue. Histamine got its name based on the fact that it can be found in various tissues ( R ). Histamine was discovered in 1910 by the winner of the 1936 Nobel Prize in Medicine, Sir Henry H. Dale ( R ). Since then, there has been a multitude of research involving histamine. However, there is still a lot we don’t know about histamine and its various functions. Histamine Production Histamine is produced from the amino acid histidine, by the enzyme HDC (histidine-decarboxylase) ( R , R ). Cells that can produce and store histamine include ( R , R , R ): Mast cel...