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Dopamine

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Dopamine is an important neurotransmitter that regulates our emotional responses, movement, pain, and the brain’s pleasure and reward center. Without dopamine, we wouldn’t be able to feel pleasure or motivation; however, it can also play a role in addiction. Introduction Dopamine is a neurotransmitter, which is a chemical released by neurons (nerve cells) to send signals to other nerve cells ( R ). Dopamine is produced in the dopaminergic neurons in the ventral tegmental area (VTA) of the midbrain, the substantia nigra pars compacta, and the arcuate nucleus of the hypothalamus ( R ). There are several distinct dopamine pathways in the brain, one of which plays a major role in reward-motivated behavior ( R ). Dopamine levels in the brain is increased by most types of rewards, and dopamine neuronal activity is increased by most addictive drugs ( R ). Dopamine has many roles in humans, which include: movement, memory, pleasure and reward, behavior and ...

49 Ways to Increase Natural Cannabinoids Without Smoking Pot (including ways that decrease cannabinoids)

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Marijuana is not the only way to activate your  cannabinoid  system.  There are more fundamental and gentle ways that help activate your  cannabinoid  system and bring you similar benefits. Top 13 Ways to Increase Cannabinoids Without Smoking Pot I don’t think it’s a coincidence that I respond well to every treatment that increases cannabinoid receptors. 1) Stress Reduction Emotional stress  decreases CB1 receptors ( R ), including social defeat stress ( R ). Prolonged exposure to elevated glucocorticoids (cortisol), such as those induced by chronic stress conditions, significantly reduces hippocampal CB1 receptors ( R ), leading to lower cannabinoid function. In fact, a recent study suggests that CB1 receptor deficiency may mimic the effects of chronic stress on emotional behavior ( R ). 2) Omega 6’s Anandamide, 2-AG, 2-AGE, and other endogenous cannabinoids are derived fr...